Evaluating the efficacy of various therapeutic modalities in advanced esophageal cancer
نویسندگان
چکیده مقاله:
Introduction: Esophageal cancer is an invasive and fatal malignancy, with the highest global incidence in southern and eastern Africa and eastern Asia. Patients with advanced localized disease and poor prognosis face a five-year survival rate of 15% to 34%. The research is aimed at evaluating Different strategies have been done to treat esophageal cancer by meta-analysis. Materials and Methods: This study was a systematic review based on valid medical databases including pubmed and medline and Google Scholar.The search was carried out with the key words of esophageal cancer and survival rate and palliative radiotherapy and chemotherapy and Neoadjuvant chemotherapy. Then all the papers that haveThe criteria for entering the study were reviewed in the last 10 years. Our search for articles in English is limited. Finally, 38 articles were reviewed. The data were analyzed using the meta-analysis method (crash effects model) and software STATA (Ver-11.1). Results: Effects of drugs such as Taxane and Irinotecan in combination with platinum and fluoropyrimidines combined with radiotherapy treatment. Which has had a moderate effect. Radiotherapy alone is used to relieve the condition normally for patients with a severe condition. Chemotherapy Together with radiotherapy in general, it has a better effect than radiotherapy alone. Brachytherapy for the insertion in comparison with metal stent to resolve the disorder Swallowing can have a better effect, longer lasting effect on the patient's esophagus. The neoadjuvant 's role in treating it is still unknown. Conclusion: 2 modalities of radiotherapy and chemotherapy have a therapeutic effect better than eachother alone. To investigate the effect of neoadjuvant chemotherapy and drugs, such as Taxon and Irinotecan, are not enough and there is a need for research in this subject.
منابع مشابه
Drooling and Various Therapeutic Modalities
ABSTRACT: Droolig or sialorrhea is a common stigmatizing problem in neurologically damaged child or adult. It is troublesome in perhaps one-third of children with cerebral palsy. Drooling occurs when there is a lack of coordinated control of facial, head and neck musculature. Various therapeutic modalities are advocated for the treatment of drooling ,such as surgical or non surgical, some of ...
متن کاملAfter introduction of advanced therapeutic medicinal products (ATMPs) in Ischemic Stroke; novel therapeutic modalities from financial perspective
Stroke, is accounting for more than 34% of total healthcare spending globally. Ischemic stroke (IS) accounts for 62.4% of incident stroke cases. IS-related direct medical expenditures place a considerable burden on healthcare system. The burden is more prominent in developing countries where limitations in insurance coverage is a big concern. It would be less challenging in developed countries,...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولInvestigating the role of signaling pathways and cancer stem cells in esophageal cancer with a therapeutic approach
Esophageal cancer (EC) is the sixth main cause of cancer death worldwide. Important genes associated with esophageal cancer include FOXO3, AKT, and GSK3β. Excessive FOXO3 expression inhibits the proliferation of cancer cells. The expression of AKT is involved in controlling cell growth in tumors. GSK3β activity is higher in cancer tissues. Given the effective role of cancer stem cells (CSCs) in...
متن کاملNonconventional therapeutic modalities in refractory angina pectoris
Abstract Despite sophisticated conventional medical treatment and the continued development and improvement of coronary revascularization modalities in recent years, a significant number of patients still suffer from refractory angina pectoris and cannot be successfully managed. Advances in therapeutic options have led to an increase in the average of life expectancy even in such ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 15 شماره Special Issue-12th. Iranian Congress of Medical Physics
صفحات 237- 237
تاریخ انتشار 2018-12-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023